Thursday, 28 April 2016

NIPER JEE-2016 for Masters' & Ph.D. Program

The dates for the most awaited exam are out. Please see the advert and note that online registration has already started. However the last date for online registration is 13th May 2016. The D-day is 12th June 2016.

Please follow the link: http://www.niper.gov.in/JEE%202016.pdf

Subscribe us for more such information and remain up to date with the happenings in Pharma world! 

Tuesday, 26 April 2016

AICTE, PCI settle regulatory discord over pharmacy education


The HRD Ministry has worked out an agreement between All India Council for Technical Education (AICTE) and Pharmacy Council of India (PCI) to settle "regulatory discord" over running of pharmacy colleges.

According to official sources, there are over 1,000 pharmacy colleges in the country which are regulated by AICTE while PCI, which comes under the Health Ministry, lays down norms for them.

"There have been instances when the two bodies are not on the same page on key matters like fixing the number of seats in colleges. It is a case of jurisdictional overlapping. Recently, the Calcutta High Court had directed the HRD Ministry to resolve the conflict between these two regulatory bodies," an official source told.

HRD Minister Secretary V S Oberoi had held a meeting with top officials of AICTE and PCI last week to discuss the issues following the high court order, the sources said.

To create greater synergy between the two bodies, it has been decided that AICTE will mandatorily incorporate PCI norms and standards in its forthcoming Approval Process Handbook, a senior official said.

Existing pharmacy institutions will be inspected by officials of both AICTE and PCI and further action can be initiated to eliminate substandard institutions.

It has also been decided that outstanding matters of pharmacy colleges should be discussed in an elaborate manner in Executive Committee meetings of AICTE to address the quality issues, the official said.

The sources said the meeting had decided to set up a committee with the members from AICTE and PCI to look into various aspects of running pharmacy colleges.

Pharma academic research - Indian patent applications published on 22nd April 2016


Every week of thousands of patent applications are published in India. The patent applications filed by the pharma academic research institutes in India go un-noticed.

We publish a list of Indian applications published related to pharma academics. This would provide us an idea about the kind of academic research being carried out in these institutes. For details of these patents, please write back to us at pharmaliterati@gmail.com

iPHEX-2016


Thursday, 21 April 2016

Share your experience_Networking at Conferences like a Pro by Raeesa Gupte

We started with the share your experience initiative recently.


Herein we post another piece of experience by Ms. Raeesa Gupte, who is currently working as an academic post-doc at University of Kansas Medical Center. She has obtained her B. Pharma from university of Mumbai and MS and PhD from US. Her profile can be accessed here: https://www.linkedin.com/in/raeesagupte




Networking at Conferences like a Pro!
Last year I attended the Society for Neuroscience (SfN) meeting in Chicago. I had just graduated, was looking for a job and was attending the conference on my personal funds. So I was super-motivated to charm everybody I met till they offered me a job! There was only one problem. I was an introvert who didn’t know the first thing about networking. So I did what we academics are best at – I did some research. I read articles from Forbes, The Muse, The Cheeky Scientist Association, Careeralism, The New York Times and everything else I could possibly find on the internet that looked like a credible source. Then I came up with a strategy so I could successfully network my way through the conference. This is an overview of what I read combined with my personal experiences:

Plan and prioritize: It is easy to get overwhelmed by the deluge of posters and symposia at a large national conference. SfN was awesome because they had a mobile app that I could use to navigate my way through the five days without losing my sanity. Because I was interested in an industry position as a research scientist at the time, I decided to stake out all the symposia and posters being presented by pharmaceutical companies. A simple search of the company name in the app allowed me to see when and where industry talks and posters were going to be held. A couple of days prior to the start of the conference I planned my schedule also factoring in the amount of time it would take me to walk between venues.

Speak up: Show up to a talk early if you can and always sit in the front. This will not only help you get noticed but will also force you to pay attention instead of doodling away. Even if you are delayed and the talk has already started, chances are you will find a few empty seats in the front because people usually like to huddle in the back. When it is time for the Q&A session in the end, introduce yourself and ask your question. No matter how silly you think it is, always speak up! It is easy for people to miss you in a crowd but when you ask a question they notice you. And more often than not, they will remember you. Poster sessions also allow you to make new connections and it might be easier breaking the ice because the person is already talking to you!

Get business cards made: The first time I went to a networking event I became acutely aware of the fact that I did not have a business card. It made me look unprepared and unprofessional. There was also no way for the people I met to connect with me after the event was over. The first thing I did after I got home that day was design and order business cards online. Make sure your name, phone number and e-mail address is clearly legible. Instead of leaving the back blank, you can use it to highlight your skills and interests. This will humanize you and make sure that you don’t get relegated to the pile of business cards that never get a second look.

Be an active listener: Being an introvert, my greatest fear was that I would end up being tongue-tied in front of new people. A few networking events later I realized that people loved talking about themselves and that provided me with enough fodder to ask them a few questions. All I had to do was be attentive to what they were saying, which I was good at anyways! After the conversation I would jot down a few interesting things about them on the back of their business cards so I would know where to pick up the next time.

Have some fun: Most big conferences have an industry-sponsored social hour in the evening. I would highly recommend attending those. Not only do you get to make industry contacts but you actually get some decent appetizers and drinks. There’s no reason why networking shouldn’t be fun after all! Hanging out near the food will ensure that you will meet a lot of people and also have something to talk about. You can also mention an interesting seminar you attended during the day as an icebreaker. The vendor booths are another excellent networking opportunity. The company reps there are happy to chat with you as long as they get to scan your badge. You can get to know of unadvertised open positions and company culture from talking to them. And you also get to collect freebies in the process!

Follow up: All the effort you put into connecting with a new person will amount to nothing if you do not follow up with them. Shoot them an email after the event (preferably the same day while you are still fresh in their memory) telling them you enjoyed your conversation. Based on what you learned about them, provide them with something that would add value for them. For e.g., if the person was interested in sports cars you could send them a magazine article about the latest BMW sports model. It doesn’t have to be life-changing but they will appreciate the fact that you remembered the little detail about them and tried to help. The idea is not to get a referral immediately; you need to build a rapport first. Don’t expect them to offer you a job based on one meeting. Keep adding value to them and eventually they will return the favour.

So at your next major conference, don’t be a socially awkward lab rat. Be the affable scientist!

The article was originally published at:
(Republished with the permission of the author).
 


Wednesday, 20 April 2016

Pharma academic research - Indian patent applications published on 15th April 2016


Every week of thousands of patent applications are published in India. The patent applications filed by the pharma academic research institutes in India go un-noticed.

We publish a list of Indian applications published related to pharma academics. This would provide us an idea about the kind of academic research being carried out in these institutes. For details of these patents, please write back to us at pharmaliterati@gmail.com


Invention
Application No
Inventors
Institute
A novel oral formulation for cancer therapy, loaded in a slow release matrix for targeted delivery
2895/DEL/2014A
1) Amlan Chakraborty
2) Pranav Patni
3) Dr. SS Lahiri
Amity University
Preparation method of delay release multi-drugs component oral disintegrate tablets for cough
2159/DEL/2014A
1) Tulshi Chakraborty
2) Vipin Saini
3) Sumeet Gupta
4) Sakshi Sharma
MM College of Pharmacy, Maharishi Markandeshwar University, Ambala, Haryana
A novel 5-[(2,4,6,-trioxotetrahydropyrimidin-5(2H)-ylidene)methyl] - furan-2-sulfonic acid compound in tubercular therapy
3122/CHE/2012A
1) A. Jerad Suresh
2) A. Manikandan
College of Pharmacy, Madras Medical College, Chennai.

Tuesday, 19 April 2016

Future of drugs-Heart Disease & Stroke_K-134

Drug Name
K-134
Structure
 Figure JPOXMLDOC01-appb-C000001
Drug Code
K-134
Synonym
OPC-33509
1-cyclopropyl-1-(2-hydroxycyclohexyl)-3-[3-[(2-oxo-1H-quinolin-6-yl)oxy]propyl]urea
Molecular Formula
C22H29N3O4
Innovator
D. Western Therapeutics Institute
Kowa Company, Ltd.
Condition
Arteriosclerosis obliterans
Mechanism of Action
Type 3 cyclic nucleotide phosphodiesterase inhibitors (PDE3 inhibitor)
Clinical Phase
IIb in US

Future of drugs-Heart Disease & Stroke_Vernakalant

Drug Name
Vernakalant
Structure
 
Drug Code
RSD1235
Synonym
Kynapid, Brinavess
(3R)-1-{(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy] cyclohexyl}pyrrolidin-3-ol
Molecular Formula
C20H31NO4
Innovator
Cardiome Pharma Corp
Merck
Condition
Prevention of post-operative atrial fibrillation in patients undergoing coronary artery bypass graft surgery.
Mechanism of Action
Blocks atrial potassium and sodium channels
Clinical Phase
Not yet approved. (Filed for Orphan Drug Designation)
Approved in Europe.

Future of drugs-Heart Disease & Stroke_Etripamil

Drug Name
Etripamil
Structure
 
Drug Code
MSP-2017
Synonym
methyl 3-(2-{[(4S)-4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl](methyl)amino}ethyl)benzoate
Molecular Formula
C27H36N2O4
Innovator
Milestone Pharmaceuticals
Condition
Acute episodes of paroxysmal supraventricular tachycardia
Mechanism of Action
Calcium channel antagonist (Intranasal)
Clinical Phase
II in USA

Future of drugs-Heart Disease & Stroke_Eleclazine

Drug Name
Eleclazine
Structure
 Click here for structure editor
Drug Code
GS-6615
Synonym
4-(pyrimidin-2-ylmethyl)-7-[4-(trifluoromethoxy) phenyl]-2,3-dihydro-1,4-benzoxazepin-5-one
Molecular Formula
C21H16F3N3O3
Innovator
Gilead Sciences
Condition
Cardiomyopathy
Mechanism of Action
Sodium channel antagonists
Clinical Phase
III in USA

Share your experience_ By Saloni Daftardar

In response to our ‘Share your experience’ initiative, Saloni Daftardar kindly agreed to write a post for us. She is an MS Candidate at College of Pharmacy of the Toledo University, Ohio.

The Grad School: Journey So Far…
Today, research is an international pursuit which has opened myriad of opportunities for us, students, to explore and invent new ideas which will provide an impetus to opening the boundaries in drug development and drive the needed breakthroughs. Once we choose to study abroad, we get our own share of experiences and challenges that make this “journey”, exciting, difficult but highly rewarding. Here are some of the lessons I learnt as I march forward in my journey as a pharmacy student in US.

The curriculum
The first year of school primarily focuses on laying a foundation for Industrial Pharmacy with courses such as advanced drug delivery systems, physical pharmacy, toxicokinetics, dosage form design and advanced analytical techniques. I have realised that more than just gaining knowledge, this foundational understanding of concepts enables seamless communication related to the subject. The curriculum also has biostatistics as a mandatory subject. Being a pharmacy student (it is implied that we are not maths lovers!), it was quite dreadful to accept the fact that I had to take this subject; but now, I cannot be happier that I learnt such an interesting and important course! Research is incomplete without statistically analysing the observed data. That’s how the term “statistically significant” makes a whole lot of difference.

The Lab
Our lab deals with solid state chemistry, pre-formulation, dosage form design pertaining to novel drug delivery systems. Application of theory-to-practice is strongly enforced here. I had to select my research topic (some advisors give you one). This can be daunting but can help you inculcate the ability of processing the work done by others in some relevant direction. This involves processing the available information, critical analysis of the hypothesis and methods and effectively implementing this data to support your new ideas. One such area that intrigued me was taste masking. Taste masking of bitter drugs has been a crucial area of research. Newer techniques and novel excipients to mask the bitter taste of an API are being explored. I have realised that focussing only on the pharmaceutical aspects for dosage form innovation isn’t enough; using the appropriate technology in order to achieve the desired results is the need of the hour. Like how amazed I was to know that an intensely bitter drug could be taste masked using nanospun mats by appropriately engineered electrospinning device!

Advisor – He is the Boss!
One of the most crucial factors of a successful grad study is the mentoring and guidance that we receive from the graduate advisor. Knowing what the advisor expects from you well in advance is more important than assessing the skills that you will learn in the grad school or the career prospects later. It’s important to know the advisor’s research area, expected work habits (current graduate students provide these details), background skills and experience. Effective communication with the advisor plays a decisive role of how our graduate journey and life thereafter would be. So, one must do his homework well! It requires a great deal of planning. As such, if you want to pursue a career in pharmaceutical industry after your graduate school, it is perfectly fine to talk (Ask, and you shall receive!) about this with your advisor before starting the research so that your project can be groomed in that direction, may be, using some techniques or software which may be a prerequisite skillset for getting a job in the industry.  Thus, a productive student-advisor relationship is a vital aspect of smooth and successful grad life.

Money matters!
There are numerous scholarships, fellowships, travel grants and so on, available for students. I have made myself habituated to browsing for such offers on a timely basis. Sometimes in order to be eligible for such financial aid, you are expected to write grants or present your work in form of abstracts or posters. Here, it is important to maintain a GPA of 3.0 out of 4. So, it is better to be on your toes to be in the race.

Networking
Our focus while doing research should be on publishing the data in form of journals or posters at various conferences. Be it academics or industry, you need to market your skills. This is one thing that I got to learn from my fellow mates. Proper documentation, presentation and effective interpersonal skills are the three fundamentals to excel in the system of innovation. These days, networking has become much more important than just building your resume. Attending conferences is the best opportunity to reach out to concerned people in academia and industry. So, make sure you take your CV and business cards along!

Degree is essential but Internship makes a difference
To make the process of fetching a job in pharmaceutical industry little easier, working as an intern to gain practical experience can prove to be helpful. Sometimes, your choice of school or university and its location are decisive factors in getting such internships as pharmaceutical industries are mostly located in regions or pockets, (mainly East Coast in North America) which prefer students from nearby schools. During the internships, one can actually understand the work culture which is something much more essential to comprehend than gaining hands-on experience. We, students, should use this platform to the best of our capabilities to establish relations with the mentors in industry and network thereby making our chances of getting our dream job or a PhD in a reputed school.

Think out-of-the-box
Today’s industry has become stagnant and saturated. Having said this, there still are opportunities if you know the right direction to look for them. There is a need of people who can think out-of-the-box. There is a need to do something apart from normal coursework and curriculum. It doesn’t have to focus only on research but other activities such as developing leadership qualities in academics, knowledge of intellectual property and developing managerial skills. It is time we develop interest in such value-adding activities which can help in overall development of intellectual minds.

Explore new domains of pharmaceutical industry
As Mark Twain quotes: “Sail away from the safe harbor. Explore Dream. Discover.”
Apart from the backbone of pharmacy, that is, pharmaceutical sciences, there are several other pharmaceutical arenas that are gaining importance in industry. Now-a-days, field of pharmacosocioeconomics and health outcomes has received immense limelight in the West. It applies the methodologies to develop, implement, and evaluate programs that lower healthcare costs and improve outcomes. The definitions are changing, and we need to change in order to be in the race. Be well read and be smart! 



Kudos to Saloni for writing such a wonderful blog post. It not only showcases the important aspects of MS in the USA, but also gives you essential tips about survival. As students, we often tend to ignore small things which can prove to be crucial later. Hence, Saloni’s post can prove to be very helpful for all the students who are pursuing their MS or about to start their MS programs.
We invite more and more such students to write about their experiences in pursuing their Masters program.